Cyfluthrin

• Description:

  Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture, veterinary, insecticide, pyrethroid and stored product[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H300+H330, H362, H370, H410

• Target:

  Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cyfluthrin.html

• Purity:

  99.52

• Solubility:

  DMSO : ≥ 200 mg/mL

• Smiles:

  O=C(C1C(C)(C)C1/C=C(Cl)\Cl)OC(C#N)C2=CC=C(F)C(OC3=CC=CC=C3)=C2

• Molecular Formula:

  C22H18Cl2FNO3

• Molecular Weight:

  434.29

• Precautions:

  H300+H330, H362, H370, H410

• References & Citations:

  [1]Jin-Sung Choi, et al.Structure-activity Relationships for the Action of 11 Pyrethroid Insecticides on Rat Na v 1.8 Sodium Channels Expressed in Xenopus Oocytes.Toxicol Appl Pharmacol. 2006 Mar 15;211 (3) :233-44|[2]María-Aránzazu Martínez, et al. Oxidative Stress and Related Gene Expression Effects of Cyfluthrin in Human Neuroblastoma SH-SY5Y Cells: Protective Effect of Melatonin. Environ Res. 2019 Oct;177:108579.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Nav1.8

• CAS Number:

  [68359-37-5]