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FM04

CAT: 0013-GTR19213786-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213786-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FM04 is a potent, orally bioavailable P-glycoprotein (P-gp) inhibitor with an EC50 of 83 nM. It disrupts the R262-Q1081-Q1118 pocket by interacting with Q1193 and I1115 in NBD2, uncoupling ICL2-NBD2 interactions. This inhibitor is a valuable research tool for investigating multidrug resistance in cancer models, both in vitro and in vivo.
CAS Number
1807320-40-6
Product Name Alternative
Pgp, P-gp (P-glycoprotein)
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.77% (May vary between batches)
Solubility
DMSO:55 mg/mL (132.38 mM)
Smiles
O=C1C=C (OC=2C1=CC=CC2) C3=CC=C (OCCOCCNCC4=CC=CC=C4) C=C3
Molecular Formula
C26H25NO4
Molecular Weight
415.48
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
MBS5814557FM04

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