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Muvalaplin

CAT: 0013-GTR19214013-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19214013-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Muvalaplin (LY3473329) is an orally bioavailable small molecule inhibitor of lipoprotein (a) [Lp (a) ] synthesis. It functions by disrupting the intracellular interaction between apolipoprotein (a) and apolipoprotein B-100, thereby reducing Lp (a) assembly. This mechanism supports its use in cardiovascular disease research, with studies demonstrating Lp (a) -lowering effects in both in vitro models and clinical trials.
CAS Number
2565656-70-2
Product Name Alternative
LY3473329, LY-3473329, LY 3473329, Lipoprotein (a), Muvalaplin
Field of Research
Metabolism Research
Purity
97.76% (May vary between batches)
Solubility
H2O:<0.1 mg/mL; DMSO:10 mg/mL (14.07 mM)
Smiles
[C@@H] (CC1=CC (CN (CC2=CC (C[C@H] (C (O) =O) [C@]3 (CCNC3) [H]) =CC=C2) CC4=CC (C[C@H] (C (O) =O) [C@]5 (CCNC5) [H]) =CC=C4) =CC=C1) (C (O) =O) [C@]6 (CCNC6) [H]
Molecular Formula
C42H54N4O6
Molecular Weight
710.9
Storage Conditions
-20°C
Notes
For research use only.

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M37059-01Muvalaplin
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T200452-01Muvalaplin tetrahydrochloride
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