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AZD4625

CAT: 0013-GTR19213350Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213350Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD4625 is a potent, selective, covalent allosteric inhibitor of mutant GTPase KRAS G12C with IC50 of 3 nM, inhibitor H358 cell proliferation with GI50 of 4 nM.AZD4625 is a clinical development candidate for the treatment of KRASG12C positive tumors.
Purity
0.98
Smiles
C=CC (N1C[C@H]2N (C3=C4C (OCC2) =C (Cl) [C@@] ([C@@]5=C (F) C=CC=C5O) =C (F) C4=NC=N3) C[C@H]1C) =O
Molecular Formula
C24H21ClF2N4O3
Molecular Weight
486.904
Notes
For research use only.

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