Products for Research Use Only
RegisterLogin

AZD8154

CAT: 0013-GTR19213328Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19213328Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AZD8154 is a highly potent, inhaled dual PI3Kγ/PI3Kδ inhibitor with pIC50 of 9.1 and 8.4, respectively.
CAS Number
2215022-45-8
Purity
>98%
Smiles
S (C) (C1=CC (C2=C (C) N=C (NC3=CC=CC (=N3) N3C (CCC3) =O) S2) =CC2=C1C (N (C2) [C@@H] (C) C1CC1) =O) (=O) =O
Molecular Formula
C27H29N5O4S2
Molecular Weight
551.680263280869
Notes
For research use only.

Chemical Information

Azd-8154
CAS Number2215022-45-8
PubChem CID141754136
IUPAC Name2-[(1S)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxopyrrolidin-1-yl)-2-pyridinyl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3H-isoindol-1-one
Molecular FormulaC27H29N5O4S2
Molecular Weight551.7
XLogP3.4
Topological Polar Surface Area149
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Heavy Atom Count38
Formal Charge0
Complexity1030
SMILES
CC1=C(SC(=N1)NC2=NC(=CC=C2)N3CCCC3=O)C4=CC5=C(C(=C4)S(=O)(=O)C)C(=O)N(C5)[C@@H](C)C6CC6
InChI
InChI=1S/C27H29N5O4S2/c1-15-25(37-27(28-15)30-21-6-4-7-22(29-21)31-11-5-8-23(31)33)18-12-19-14-32(16(2)17-9-10-17)26(34)24(19)20(13-18)38(3,35)36/h4,6-7,12-13,16-17H,5,8-11,14H2,1-3H3,(H,28,29,30)/t16-/m0/s1
InChIKey
XOMFDZJQLSPGGV-INIZCTEOSA-N
Chemical Structure
2D Structure
2D structure of Azd-8154
CAS: 2215022-45-8
CID: 141754136
Formula: C27H29N5O4S2
MW: 551.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight551.7
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass551.16609677
Monoisotopic Mass551.16609677
Topological Polar Surface Area149 Ų
Heavy Atom Count38
Formal Charge0
Complexity1030
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19177951-01AZD8055
GTR19171881-01AZD3514
GTR19168097-01AZD0156
GTR19168094-01AZD8186
GTR19162950-01AZD8186
GTR19198164-01AZD8542
GTR19195491-01AZD8165
GTR19257864-01AZD1134
GTR19186625-01AZD7254
GTR19236202-01AZD4144

Alternative Products

CatalogName
BA8748-1AZD8154

Popular Products