Products for Research Use Only

IC-8

CAT: 0013-GTR19213226-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213226-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IC8 is an ionizable cationic lipid. It has been used in combination with other lipids for the formation of lipid nanoparticles (LNPs) . Immunization with severe acute respiratory coronavirus 2 (SARS-CoV-2) spike glycoprotein mRNA in IC8- and manganese-containing LNPs induces IgG responses to SARS-CoV-2 Delta and Omicron variants in mice.1 Administration of mRNA encoding B7-H3 X CD3 bispecific T cell engaging (BiTE) antibodies in IC8-containing LNPs reduces tumor growth in MV4-11 and A375 mouse xenograft models.
CAS Number
2349307-32-8
Purity
>95%
Smiles
OC (CCCCCCCCCCCC) CN (CC (CCCCCCCCCCCC) O) CCCN1CCN (CCCN (CC (CCCCCCCCCCCC) O) CC (CCCCCCCCCCCC) O) CC1
Molecular Formula
C66H136N4O4
Molecular Weight
1049.8
Notes
For research use only.