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SFI003

CAT: 0013-GTR19213043-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213043-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SFI003 is a novel small molecule inhibitor of SRSF3 that induces apoptosis in colorectal cancer cells by disrupting the SRSF3/DHCR24 axis and elevating reactive oxygen species (ROS) . This compound is a valuable research tool for investigating CRC mechanisms and therapeutic strategies in both in vitro and in vivo models.
CAS Number
2361332-90-1
Product Name Alternative
ROS, apoptosis
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
98.92% (May vary between batches)
Solubility
DMSO:50 mg/mL (137.57 mM)
Smiles
C (=N\NC1=NC (=CS1) C2=CC=C (OC) C=C2) (\C) /C=3NC=4C (N3) =CC=CC4
Molecular Formula
C19H17N5OS
Molecular Weight
363.44
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-[(E)-1-(1H-benzimidazol-2-yl)ethylideneamino]-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
CAS Number2361332-90-1
PubChem CID141745171
IUPAC NameN-[(E)-1-(1H-benzimidazol-2-yl)ethylideneamino]-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
Molecular FormulaC19H17N5OS
Molecular Weight363.4
XLogP4.7
Topological Polar Surface Area103
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count26
Formal Charge0
Complexity496
SMILES
C/C(=N\NC1=NC(=CS1)C2=CC=C(C=C2)OC)/C3=NC4=CC=CC=C4N3
InChI
InChI=1S/C19H17N5OS/c1-12(18-20-15-5-3-4-6-16(15)21-18)23-24-19-22-17(11-26-19)13-7-9-14(25-2)10-8-13/h3-11H,1-2H3,(H,20,21)(H,22,24)/b23-12+
InChIKey
QGFYENXFCHRFJF-FSJBWODESA-N
Chemical Structure
2D Structure
2D structure of N-[(E)-1-(1H-benzimidazol-2-yl)ethylideneamino]-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
CAS: 2361332-90-1
CID: 141745171
Formula: C19H17N5OS
MW: 363.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight363.4
XLogP34.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass363.11538136
Monoisotopic Mass363.11538136
Topological Polar Surface Area103 Ų
Heavy Atom Count26
Formal Charge0
Complexity496
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-148660-01SFI003

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