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SFI003

CAT: 0931-T72068-04Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T72068-04Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2361332-90-1
Target
ROS, Reactive Oxygen Species, Apoptosis
Related Pathways
Immunology/Inflammation, Metabolism, Apoptosis, NF-κB
Purity
0.9944
Bioactivity
SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen species (ROS) axis.
Smiles
C(=N\NC1=NC(=CS1)C2=CC=C(OC)C=C2)(\C)/C=3NC=4C(N3)=CC=CC4
Molecular Formula
C19H17N5OS
Molecular Weight
363.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-[(E)-1-(1H-benzimidazol-2-yl)ethylideneamino]-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
CAS Number2361332-90-1
PubChem CID141745171
IUPAC NameN-[(E)-1-(1H-benzimidazol-2-yl)ethylideneamino]-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
Molecular FormulaC19H17N5OS
Molecular Weight363.4
XLogP4.7
Topological Polar Surface Area103
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count26
Formal Charge0
Complexity496
SMILES
C/C(=N\NC1=NC(=CS1)C2=CC=C(C=C2)OC)/C3=NC4=CC=CC=C4N3
InChI
InChI=1S/C19H17N5OS/c1-12(18-20-15-5-3-4-6-16(15)21-18)23-24-19-22-17(11-26-19)13-7-9-14(25-2)10-8-13/h3-11H,1-2H3,(H,20,21)(H,22,24)/b23-12+
InChIKey
QGFYENXFCHRFJF-FSJBWODESA-N
Chemical Structure
2D Structure
2D structure of N-[(E)-1-(1H-benzimidazol-2-yl)ethylideneamino]-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
CAS: 2361332-90-1
CID: 141745171
Formula: C19H17N5OS
MW: 363.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight363.4
XLogP34.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass363.11538136
Monoisotopic Mass363.11538136
Topological Polar Surface Area103 Ų
Heavy Atom Count26
Formal Charge0
Complexity496
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-148660-01SFI003

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