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Levomecol

CAT: 0804-HY-111903-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111903-02Size:25 mg
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Description
Levomecol (Chloramphenicol), made up of Chloramphenicol, Methyluracil, is a broad-spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae. Levomecol (Chloramphenicol) ) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis[1][2][3].
CAS Number
118573-58-3
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/levomecol.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1)C(Cl)Cl.O=C2NC(C(C)=CN2)=O
Molecular Formula
C16H18Cl2N4O7
Molecular Weight
449.24
References & Citations
[1]Chloramphenicol|[2]Babenkov HD, et al. [The influence of photochemically activated 40% solution of levomecol ointment toward apoptosis in muscles of the rats posterior extremities in inflammatory-purulent complications of diabetes mellitus]. Klin Khir. 2006 Jul; (7) :58-60. Ukrainian|[3]Babenkov HD, et al. [The influence of photochemically activated 40% solution of levomecol ointment toward apoptosis in muscles of the rats posterior extremities in inflammatory-purulent complications of diabetes mellitus]. Klin Khir. 2006 Jul; (7) :58-60. Ukrainian.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Levomecol

used to treat maxillofacial phlegmons; contains levomycetin & methyluracil in a polyethylene glycol base

CAS Number118573-58-3
PubChem CID3081163
IUPAC Name2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide;5-methyl-1H-pyrimidine-2,4-dione
Molecular FormulaC16H18Cl2N4O7
Molecular Weight449.2
Topological Polar Surface Area174
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count29
Formal Charge0
Complexity537
SMILES
CC1=CNC(=O)NC1=O.C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
InChI
InChI=1S/C11H12Cl2N2O5.C5H6N2O2/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20;1-3-2-6-5(9)7-4(3)8/h1-4,8-10,16-17H,5H2,(H,14,18);2H,1H3,(H2,6,7,8,9)/t8-,9-;/m1./s1
InChIKey
ZYLKCEKZZWDRSF-VTLYIQCISA-N
Chemical Structure
2D Structure
2D structure of Levomecol
CAS: 118573-58-3
CID: 3081163
Formula: C16H18Cl2N4O7
MW: 449.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight449.2
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass448.0552543
Monoisotopic Mass448.0552543
Topological Polar Surface Area174 Ų
Heavy Atom Count29
Formal Charge0
Complexity537
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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CatalogName
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