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Levomenol

CAT: 0804-HY-N6967-01Size: 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-N6967-01Size:1 mL
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Description
Levomenol ((-) -α-Bisabolol), a monocyclic sesquiterpene alcohol, exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. Levomenol also has neuroprotective effects and prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Levomenol attenuates nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain. Orally active[1][2].
CAS Number
23089-26-1
Product Name Alternative
(-) -α-Bisabolol
UNSPSC
12352211
Hazard Statement
H315, H319, H320
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/levomenol.html
Concentration
10mM
Purity
99.22
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@](O)([C@@]1([H])CCC(C)=CC1)CC/C=C(C)/C
Molecular Formula
C15H26O
Molecular Weight
222.37
Precautions
H315, H319, H320
References & Citations
[1]Fernandes MYD, et al. (-) -α-bisabolol prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Eur J Pharmacol. 2019 Jan 5;842:270-280.|[2]Melo LT, et al. (-) -α-Bisabolol reduces nociception and trigeminal central sensitisation in acute orofacial neuropathic pain induced by infraorbital nerve injury. Life Sci. 2019 Jun 15;227:122-128.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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