Products for Research Use Only

Talotrexin

CAT: 0013-GTR19212403-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212403-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Talotrexin (PT523) is a nonpolyglutamatable antifolate analog that potently and selectively inhibits the Reduced Folate Carrier (RFC) . Its primary mechanism involves targeting dihydrofolate reductase (DHFR), making it a valuable research tool for studying antifolate resistance and evaluating antitumor activity in both cellular and animal models.
CAS Number
113857-87-7
Field of Research
Cell Biology, Metabolism Research, Molecular Biology
Smiles
NC=1C2=C (N=CC (CNC3=CC=C (C (N[C@@H] (CCCNC (=O) C4=C (C (O) =O) C=CC=C4) C (O) =O) =O) C=C3) =N2) N=C (N) N1
Molecular Formula
C27H27N9O6
Molecular Weight
573.56
Storage Conditions
-20°C
Notes
For research use only.