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SMTIN-T140

CAT: 0013-GTR19212371-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212371-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SMTIN-T140 (compound 6a) is a potent TRAP1 inhibitor (IC50 = 1.646 μM) that exerts anticancer effects by disrupting mitochondrial function, increasing ROS, and activating AMPK. It has demonstrated significant in vivo antitumor efficacy in a PC3 prostate cancer xenograft model without observable toxicity.
CAS Number
2851532-40-4
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
C1=CC=C (C=C1) [P+] (CCCCCCN2C3=C (N=C (N=C3Cl) N) N (C2=O) CC4=C (C=C (C=C4) Br) F) (C5=CC=CC=C5) C6=CC=CC=C6
Molecular Formula
C36H34BrClFN5OP+
Molecular Weight
718.02
Storage Conditions
-20°C
Notes
For research use only.

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T70270-01SMTIN-P01

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