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RO5461111

CAT: 0013-GTR19212303-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212303-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RO5461111 is a potent and selective oral Cathepsin S inhibitor, demonstrating sub-nanomolar IC50 values against both human and murine enzymes. It effectively inhibits antigen-specific T and B cell activation and has shown efficacy in ameliorating pulmonary inflammation and lupus nephritis in preclinical models, making it a valuable tool for immunology and autoimmune disease research.
CAS Number
1252637-46-9
Field of Research
Protein Biochemistry
Smiles
C (=O) (C1 (C (F) (F) F) CC1) N2[C@H] (C (NC3 (C#N) CC3) =O) C[C@@H] (S (=O) (=O) C4=C (C (F) (F) F) C=C (C=C4) C=5C=C (C) N=CC5) C2
Molecular Formula
C27H24F6N4O4S
Molecular Weight
614.56
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T73220-01RO5461111

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