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Epofolate

CAT: 0013-GTR19211649-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19211649-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS753493 is a folate receptor-targeted prodrug of epothilone, delivering its antimitotic payload into cancer cells overexpressing this receptor. Upon internalization, it stabilizes microtubules, inhibiting cell division. This targeted mechanism has been investigated in preclinical in vitro and in vivo models for various solid tumors.
CAS Number
958646-17-8
Field of Research
Cell Biology
Smiles
C (COC (OCCSSC[C@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC (CC[C@H] (NC (=O) C1=CC=C (NCC=2N=C3C (NC2) =NC (N) =NC3=O) C=C1) C (O) =O) =O) CC (O) =O) =O) CCCNC (=N) N) =O) CC (O) =O) =O) C (O) =O) =O) N4[C@@]5 ([C@]4 (CCC[C@H] (C) [C@H] (O) [C@@H] (C) C (=O) C (C) (C) [C@@H] (O) CC (=O) O[C@H] (\C (=C\C=6N=C (C) SC6) \C) C5) [H]) [H]
Molecular Formula
C67H92N16O22S3
Molecular Weight
1569.74
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T68232-01Epofolate

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