SY-640

• Description:

  SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/sy-640.html

• Concentration:

  10mM

• Purity:

  99.77

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(N(C)CC1=CC2=C(OCO2)C=C1)=O

• Molecular Formula:

  C11H13NO3

• Molecular Weight:

  207.23

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Y Tanaka, et al. Hepatoprotective effect of SY-640, a novel acetamide derivative, on Propionibacterium acnes and lipopolysaccharide-induced liver injury in mice. Arch Int Pharmacodyn Ther. Mar-Apr 1995;329 (2) :319-30.|[2]P F Li, et al. [Inhibitory effect of 2- (N-acetyl-methyl amino) -3',4'-methylenedioxyacetyl-aminophene (SY-640) on covalent binding of carcinogenic benzo (a) pyrene with mouse hepatocyte nuclear DNA]. Yao Xue Xue Bao. 1997 Sep;32 (9) :663-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [168705-70-2]