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APcK110

CAT: 0013-GTR19208543-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208543-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
APcK110 is a novel, potent Kit inhibitor that suppresses proliferation in mastocytosis and AML cell lines by dose-dependently inhibiting Kit phosphorylation and downstream Stat3, Stat5, and Akt signaling. Its superior potency compared to imatinib and dasatinib in models like OCI/AML3 supports its research application in acute myeloid leukemia (AML) therapeutics.
CAS Number
1001083-74-4
Field of Research
Signal Transduction
Smiles
FC1=CC=C (C=2C=3C (=NC (=CC3) C4=CC (OC) =CC (OC) =C4) NN2) C=C1
Molecular Formula
C20H16FN3O2
Molecular Weight
349.36
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-110071APcK110

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