Products for Research Use Only

Carotegrast methyl HCl

CAT: 0013-GTR19208451-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208451-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carotegrast methyl (AJM300/PTC-100) is an orally bioavailable α4 integrin antagonist that inhibits leukocyte trafficking. It has demonstrated dose-dependent efficacy in preclinical models, including the reduction of lymphocyte homing to gut-associated lymphoid tissue and the prevention of experimental colitis in mice.
CAS Number
1338380-52-1
Field of Research
Signal Transduction
Smiles
Cl.COC (=O) [C@H] (Cc1ccc (cc1) -n1c (=O) n (C) c2ccc (cc2c1=O) N (C) C) NC (=O) c1c (Cl) cccc1Cl
Molecular Formula
C25H20Cl3N3O5
Molecular Weight
548.801
Storage Conditions
-20°C
Notes
For research use only.