Products for Research Use Only

Carotegrast methyl

CAT: 0013-GTR19171489-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171489-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carotegrast methyl (AJM300) is an orally bioavailable small molecule antagonist that selectively targets both α4β1 and α4β7 integrins. It is a research tool for investigating integrin function in inflammatory and autoimmune diseases, with demonstrated utility in both in vitro adhesion assays and in vivo models of colitis.
CAS Number
401905-67-7
Product Name Alternative
AJM 300, AJM300, AJM-300, Carotegrast methyl, colitis, Inhibitor, Integrin, HCA2969, inhibit, Jurkat, orally, TK-1, RPMI-8866, α4β1 integrin
Field of Research
Signal Transduction
Purity
98.73% (May vary between batches)
Solubility
DMSO:100 mg/mL (175.61 mM)
Smiles
COC (=O) [C@H] (Cc1ccc (cc1) -n1c (=O) n (C) c2ccc (cc2c1=O) N (C) C) NC (=O) c1c (Cl) cccc1Cl
Molecular Formula
C28H26Cl2N4O5
Molecular Weight
569.44
Storage Conditions
-20°C
Notes
For research use only.