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PBT434 HBr

CAT: 0013-GTR19208210-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208210-01Size:25 mg
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Description
PBT434 is a brain-penetrant small molecule inhibitor of α-synuclein aggregation that functions by redistributing reactive iron. In vivo studies in transgenic models of Parkinson's disease and MSA demonstrated reduced protein aggregates, neuronal protection, and improved motor function. This makes it a valuable research tool for investigating synucleinopathies and iron-mediated neurotoxicity.
CAS Number
1232841-78-9
Smiles
Br.CCNCc1nc2c (O) c (Cl) cc (Cl) c2c (=O) n1C
Molecular Formula
C12H14BrCl2N3O2
Molecular Weight
383.07
Storage Conditions
-20°C
Notes
For research use only.

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HY-120475-01PBT434
T71174-01PBT434 HBr
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HY-120475A-01PBT434 (mesylate)
HY-120475BPBT434 (free base)

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