Products for Research Use Only

AZD-8418

CAT: 0013-GTR19208119-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208119-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD8418 and AZD8529 are positive allosteric modulators of the mGlu2 receptor, demonstrating efficacy in reducing nicotine self-administration and seeking in preclinical models. Their selective inhibition of nicotine- versus food-maintained behavior, along with effects on cue-induced reinstatement, supports research into glutamate modulation for substance use disorders.
CAS Number
1198309-73-7
Smiles
O=C1C=2C (CN1[C@@H] (C) C3CC3) =CC (=CC2Cl) C4=CC (C (N (C) C) =O) =NO4
Molecular Formula
C19H20ClN3O3
Molecular Weight
373.83
Storage Conditions
-20°C
Notes
For research use only.