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AZD-5672

CAT: 0013-GTR19171537-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171537-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD-5672 is a potent CCR5 antagonist (IC50 = 0.32 nM) investigated for rheumatoid arthritis. It also exhibits off-target activity, inhibiting hERG binding and P-gp transport at micromolar concentrations. This small molecule is a tool for in vitro and in vivo studies of chemokine receptor function and inflammatory disease models.
CAS Number
780750-65-4
Product Name Alternative
P-gp, Pgp, UNII-61XQN688TW, hERG, AZD 5672, AZD5672, AZD-5672, CCR5
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Purity
95.58% (May vary between batches)
Solubility
DMSO:30 mg/mL (47.41 mM)
Smiles
CCN (C1CCN (CC[C@H] (c2ccc (cc2) S (C) (=O) =O) c2cc (F) cc (F) c2) CC1) C (=O) Cc1ccc (cc1) S (C) (=O) =O
Molecular Formula
C32H38F2N2O5S2
Molecular Weight
632.78
Storage Conditions
-20°C
Notes
For research use only.

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