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CFM-2

CAT: 0013-GTR19206253-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206253-01Size:25 mg
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Description
CFM-2 is a potent and selective non-competitive AMPA receptor antagonist. It demonstrates robust anticonvulsant efficacy in diverse in vivo seizure models, making it a valuable research tool for studying excitatory neurotransmission and epilepsy pathophysiology.
CAS Number
178616-26-7
Product Name Alternative
CFM 2, CFM2, CFM-2, AMPAR
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.16% (May vary between batches)
Solubility
DMSO:45 mg/mL (144.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.42 mM)
Smiles
COc1cc2CC (=O) NN=C (c3ccc (N) cc3) c2cc1OC
Molecular Formula
C17H17N3O3
Molecular Weight
311.34
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Cfm-2

1-(4-aminophenyl)-7,8-dimethoxy-3,5-dihydro-2,3-benzodiazepin-4-one is a benzodiazepine.

CAS Number178616-26-7
PubChem CID4377504
IUPAC Name1-(4-aminophenyl)-7,8-dimethoxy-3,5-dihydro-2,3-benzodiazepin-4-one
Molecular FormulaC17H17N3O3
Molecular Weight311.33
XLogP1
Topological Polar Surface Area85.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count23
Formal Charge0
Complexity460
SMILES
COC1=C(C=C2C(=C1)CC(=O)NN=C2C3=CC=C(C=C3)N)OC
InChI
InChI=1S/C17H17N3O3/c1-22-14-7-11-8-16(21)19-20-17(13(11)9-15(14)23-2)10-3-5-12(18)6-4-10/h3-7,9H,8,18H2,1-2H3,(H,19,21)
InChIKey
MJKADKZSYQWGLL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cfm-2
CAS: 178616-26-7
CID: 4377504
Formula: C17H17N3O3
MW: 311.33
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight311.33
XLogP31
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass311.12699141
Monoisotopic Mass311.12699141
Topological Polar Surface Area85.9 Ų
Heavy Atom Count23
Formal Charge0
Complexity460
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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HY-12503RCFM-2 (Standard)
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