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CFM-1

CAT: 0013-GTR19200478-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19200478-01Size:25 mg
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Description
CFM-1 is a small molecule antagonist that inhibits the anaphase-promoting complex (APC/C) and disrupts its interaction with CARP-1. This compound is a valuable research tool for studying cell cycle regulation, apoptosis, and mitotic exit in both cellular and biochemical assays.
CAS Number
1380448-60-1
Field of Research
Cell Biology
Smiles
CC1=CC (Br) =CC2=C1NC (=O) \C2=C1/SC (=S) NC1=O
Molecular Formula
C12H7BrN2O2S2
Molecular Weight
355.23
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(5Z)-5-(5-bromo-7-methyl-2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
CAS Number1380448-60-1
PubChem CID1377592
IUPAC Name5-bromo-3-(4-hydroxy-2-sulfanylidene-3H-1,3-thiazol-5-yl)-7-methylindol-2-one
Molecular FormulaC12H7BrN2O2S2
Molecular Weight355.2
XLogP2.1
Topological Polar Surface Area119
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count19
Formal Charge0
Complexity699
SMILES
CC1=CC(=CC2=C(C(=O)N=C12)C3=C(NC(=S)S3)O)Br
InChI
InChI=1S/C12H7BrN2O2S2/c1-4-2-5(13)3-6-7(10(16)14-8(4)6)9-11(17)15-12(18)19-9/h2-3,17H,1H3,(H,15,18)
InChIKey
LOVNGMHIRITVRG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (5Z)-5-(5-bromo-7-methyl-2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
CAS: 1380448-60-1
CID: 1377592
Formula: C12H7BrN2O2S2
MW: 355.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight355.2
XLogP32.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass353.91323
Monoisotopic Mass353.91323
Topological Polar Surface Area119 Ų
Heavy Atom Count19
Formal Charge0
Complexity699
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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