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CNX-500

CAT: 0013-GTR19206182-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206182-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CNX-500 is a biotinylated covalent probe that potently and selectively inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 0.5 nM. This tool compound is useful for studying Btk function and occupancy in both cellular and in vivo models, with minimal off-target effects on EGFR and Src-family kinases.
CAS Number
1202758-21-1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
[H][C@]12CS[C@@H] (CCCCC (=O) NCCCOCCOCCOCCCNC (=O) CCCC (=O) NCCCOc3cccc (Nc4ncc (C) c (Nc5cccc (NC (=O) C=C) c5) n4) c3) [C@@]1 ([H]) NC (=O) N2
Molecular Formula
C48H68N10O9S
Molecular Weight
961.18
Storage Conditions
-20°C
Notes
For research use only.

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