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CNX-774

CAT: 0013-GTR19173980-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173980-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CNX-774 is a potent, orally bioavailable, and irreversible small molecule inhibitor of Bruton's tyrosine kinase (BTK) with sub-nanomolar inhibitory activity. It is a valuable research tool for investigating BTK-dependent signaling pathways in both cellular assays and animal models of autoimmune diseases and B-cell malignancies.
CAS Number
1202759-32-7
Product Name Alternative
Inhibitor, inhibit, CNX774, CNX-774, CNX 774, autoimmune, Bruton tyrosine kinase, BTK, Btk, B-cell, BCR
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
97.35% (May vary between batches)
Solubility
Ethanol:2 mg/mL (4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.61 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (186.19 mM)
Smiles
CNC (=O) c1cc (Oc2ccc (Nc3ncc (F) c (Nc4cccc (NC (=O) C=C) c4) n3) cc2) ccn1
Molecular Formula
C26H22FN7O3
Molecular Weight
499.5
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
B1408-5CNX-774
A13233-100CNX-774 100mg
A13233-50CNX-774 50mg
A13233-2CNX-774 2mg
A13233-500CNX-774 500mg
A13233-10CNX-774 10mg
A13233-1CNX-774 1mg
A13233-25CNX-774 25mg
A13233-5CNX-774 5mg
2600-25BTK Inhibitor, CNX-774

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