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DM4-SMe

CAT: 0013-GTR19206032-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206032-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DM4-SMe is a cytotoxic metabolite of antibody-maytansinoid conjugates (AMCs) and a potent tubulin inhibitor. With an IC50 of 0.026 nM in KB cells, it is a key payload for ADC research, enabling studies on targeted cancer therapy in both in vitro and in vivo experimental models.
CAS Number
796073-68-2
Field of Research
Signal Transduction
Smiles
[H][C@@]12C[C@@] (O) (NC (=O) O1) [C@] ([H]) (OC) \C=C/C=C (C) \Cc1cc (OC) c (Cl) c (c1) N (C) C (=O) C[C@] ([H]) (OC (=O) [C@H] (C) N (C) C (=O) CCC (C) (C) SSC) [C@]1 (C) O[C@H]1[C@@H]2C
Molecular Formula
C39H56ClN3O10S2
Molecular Weight
826.46
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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WGB07368-01DM4-SMe
BA2343-50DM1-SMe
WGB07370-01DM3-SMe
A15960-100DM1-Sme 100mg
A15960-25DM1-Sme 25mg
A15960-5DM1-Sme 5mg
A15960-1DM1-Sme 1mg
HY-100128RDM1-SMe (Standard)
BLG-M0436-SMe-PuR
A15960-50DM1-Sme 50mg

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