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DM4-SMCC

CAT: 0013-GTR19259489Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259489Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
​​DM4-SMCC​​ is an ​​antibody-drug conjugate (ADC) payload​​ that combines the potent ​​antitubulin agent DM4​​ with a ​​non-cleavable SMCC linker​​. This conjugate is designed to deliver cytotoxic effects specifically to tumor cells, leveraging DM4's ability to disrupt microtubule dynamics. The stable SMCC linker ensures controlled drug release, enhancing the ADC's ​​antitumor activity​​ while minimizing off-target toxicity.
CAS Number
1228105-52-9
Purity
>98%
Smiles
ClC1C (=CC2CC (C) =CC=C[C@H] ([C@]3 (C[C@@H] ([C@@H] (C) [C@H]4[C@] (C) ([C@H] (CC (N (C) C=1C=2) =O) OC ([C@H] (C) N (C) C (CCC (C) (C) SC1CC (N (C1=O) CC1CCC (C (=O) ON2C (CCC2=O) =O) CC1) =O) =O) =O) O4) OC (N3) =O) O) OC) OC |c:7,9|
Molecular Formula
C54H72CLN5O16S
Molecular Weight
1114.69139385223
Notes
For research use only.

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