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S-methyl DM1

CAT: 0013-GTR19204877-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204877-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S-methyl DM1 is a thiomethyl derivative of the cytotoxic agent Maytansine, functioning as a potent tubulin-binding inhibitor with a Kd of 0.93 μM to disrupt microtubule assembly. This activity makes it a valuable tool compound for investigating antimitotic mechanisms and cytotoxicity in cancer cell biology research, both in vitro and in preclinical models.
CAS Number
912569-84-7
Field of Research
Signal Transduction
Smiles
C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCSC) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]
Molecular Formula
C36H50ClN3O10S
Molecular Weight
752.31
Storage Conditions
-20°C
Notes
For research use only.

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