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AZD0156

CAT: 0804-HY-100016-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100016-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits the ATM-mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis[1].
CAS Number
[1821428-35-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; ATM/ATR
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/AZD0156.html
Purity
99.83
Smiles
O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3
Molecular Formula
C26H31N5O3
Molecular Weight
461.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer.?
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
ATM

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MBS384290-01AZD0156
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A16419-5AZD0156 5mg
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