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AGI-24512

CAT: 0013-GTR19204087-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204087-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AGI-24512 is a potent and selective MAT2A inhibitor (IC50: 8 nM) with antiproliferative effects in MTAP-deficient cancer cells. Its mechanism, which induces DNA damage, supports its use in both in vitro and in vivo studies exploring novel combination therapies for oncology research.
CAS Number
2201066-53-5
Product Name Alternative
S-adenosylmethionine Synthetase, PRMT5, HCT116, MAT2A, MATA2, MTAP, methylthioadenosine phosphorylase, Methionine Adenosyltransferase (MAT), anticancer, antiproliferative, AGI 24512, AGI24512, AGI-24512, DNA damage response, DNA
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.55% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.24 mM) ; DMSO:80 mg/mL (199.77 mM) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
Cc1[nH]c2c (N3CCCCC3) c (nn2c (=O) c1-c1ccc (O) cc1) -c1ccccc1
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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BA173349-01AGI 24512
E1806-100mgAGI-24512
A20237-50AGI-24512 50mg
A20237-25AGI-24512 25mg
A20237-100AGI-24512 100mg
A20237-1AGI-24512 1mg

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