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CHMFL-BTK-01

CAT: 0013-GTR19203500-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203500-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CHMFL-BTK-01 is a potent and irreversible Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 7 nM, effectively suppressing its Y223 autophosphorylation. This compound is a valuable chemical probe for studying BTK-dependent signaling in B-cell malignancies and autoimmune disease models, both in cellular and in vivo contexts.
CAS Number
2095280-64-9
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (=O) (C1=C (NC (C=C) =O) C=C (NC2=CC (=CN (C) C2=O) C3=C (C) C (NC (=O) C4=CC=C (C (C) (C) C) C=C4) =CC=C3) C=C1) N5CCOCC5
Molecular Formula
C38H41N5O5
Molecular Weight
647.76
Storage Conditions
-20°C
Notes
For research use only.

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