Products for Research Use Only

PF-610355

CAT: 0013-GTR19203272-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203272-02Size:5 mg
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Description
PF-610355 is a potent and long-acting β2-adrenergic receptor agonist with an EC50 of 0.26 nM. It serves as a valuable research tool for investigating respiratory diseases such as asthma and COPD, with utility in both in vitro receptor studies and in vivo models of bronchoconstriction.
CAS Number
862541-45-5
Product Name Alternative
Adrenergic Receptor, AdrenergicReceptor, β2-adrenergic receptor, PF 610355, PF-00610355, PF-610,355, PF610355, PF-610355
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.73% (May vary between batches)
Smiles
C (NC (CC1=CC (CC (NC[C@H] (O) C2=CC (NS (C) (=O) =O) =C (O) C=C2) (C) C) =CC=C1) =O) C=3C=C (C=CC3) C4=CC=C (O) C=C4
Molecular Formula
C34H39N3O6S
Molecular Weight
617.76
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-((4'-Hydroxy(1,1'-biphenyl)-3-yl)methyl)-3-(2-(((2R)-2-hydroxy-2-(4-hydroxy-3-((methylsulfonyl)amino)phenyl)ethyl)amino)-2-methylpropyl)benzeneacetamide

PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.

CAS Number862541-45-5
PubChem CID11505444
IUPAC Name2-[3-[2-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(methanesulfonamido)phenyl]ethyl]amino]-2-methylpropyl]phenyl]-N-[[3-(4-hydroxyphenyl)phenyl]methyl]acetamide
Molecular FormulaC34H39N3O6S
Molecular Weight617.8
XLogP3.8
Topological Polar Surface Area156
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count13
Heavy Atom Count44
Formal Charge0
Complexity995
SMILES
CC(C)(CC1=CC=CC(=C1)CC(=O)NCC2=CC(=CC=C2)C3=CC=C(C=C3)O)NC[C@@H](C4=CC(=C(C=C4)O)NS(=O)(=O)C)O
InChI
InChI=1S/C34H39N3O6S/c1-34(2,36-22-32(40)28-12-15-31(39)30(19-28)37-44(3,42)43)20-24-7-4-6-23(16-24)18-33(41)35-21-25-8-5-9-27(17-25)26-10-13-29(38)14-11-26/h4-17,19,32,36-40H,18,20-22H2,1-3H3,(H,35,41)/t32-/m0/s1
InChIKey
YPHDIMUXXABSSO-YTTGMZPUSA-N
Chemical Structure
2D Structure
2D structure of N-((4'-Hydroxy(1,1'-biphenyl)-3-yl)methyl)-3-(2-(((2R)-2-hydroxy-2-(4-hydroxy-3-((methylsulfonyl)amino)phenyl)ethyl)amino)-2-methylpropyl)benzeneacetamide
CAS: 862541-45-5
CID: 11505444
Formula: C34H39N3O6S
MW: 617.8
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight617.8
XLogP33.8
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count13
Exact Mass617.25595715
Monoisotopic Mass617.25595715
Topological Polar Surface Area156 Ų
Heavy Atom Count44
Formal Charge0
Complexity995
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes