Human α-Thrombin

• UNSPSC Description:

  Human α-thrombin is a multifunctional serine protease that plays a pivotal role in the coagulation pathway. Human α-thrombin cleaves fibrinogen and converts it into fibrin. Human α-thrombin can stimulate platelet activation and stabilize fibrin polymers[1].

• Target Antigen:

  Thrombin

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/human-α-thrombin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Human a-Thrombin]

• References & Citations:

  [1]Troisi R, et, al. Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites. J Biomol Struct Dyn. 2021 Apr;39(6):2199-2209.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store at -80°C for 2 years

• Clinical Information:

  No Development Reported

• CAS Number:

  9002-04-4