Human Gamma Thrombin

Human Gamma Thrombin_x000D_ Catalog number: B2013733_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 mg_x000D_ Molecular Weight or Concentration: 12 kDa_x000D_ Supplied as: Powder_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: Human Gamma Thrombin_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Davie EW, Kulman JD. An overview of the structure and function of thrombin Semin Thromb Hemost. 2006 Apr;32 Suppl 1:3-15._x000D_ 2: Jandrot-Perrus M, Guillin MC, Nurden AT. Human gamma-thrombin: lack of correlation between a platelet functional response and glycoprotein V hydrolysis Thromb Haemost. 1987 Oct 28;58(3):915-20._x000D_ 3: Naldini A, Morena E, Filippi I, Pucci A, Bucci M, Cirino G, Carraro F. Thrombin inhibits IFN-gamma production in human peripheral blood mononuclear cells by promoting a Th2 profile J Interferon Cytokine Res. 2006 Nov;26(11):793-9._x000D_ 4: Brower MS, Walz DA, Garry KE, Fenton JW 2nd. Human neutrophil elastase alters human alpha_thrombin function: limited proteolysis near the gamma-cleavage site results in decreased fibrinogen clotting and platelet-stimulatory activity Blood. 1987 Mar;69(3):813-9._x000D_ 5: Bezeaud A, Denninger MH, Guillin MC. Interaction of human alpha_thrombin and gamma_thrombin with antithrombin III, protein C and thrombomodulin Eur J Biochem. 1985 Dec 16;153(3):491-6._x000D_ 6: Rydel TJ, Yin M, Padmanabhan KP, Blankenship DT, Cardin AD, Correa PE, Fenton JW 2nd, Tulinsky A. Crystallographic structure of human gamma_thrombin J Biol Chem. 1994 Sep 2;269(35):22000-6._x000D_ 7: Soslau G, Prest PJ, Class R, Jost M, Mathews L. Inhibition of gamma_thrombin-induced human platelet aggregation by histone H1subtypes and H1.3 fragments Platelets. 2009 Aug;20(5):349-56._x000D_ 8: Witting JI, Miller TM, Fenton JW 2nd. Human alpha- and gamma_thrombin specificity with tripeptide p-nitroanalide substrates under physiologically relevant conditions Thromb Res. 1987 May 15;46(4):567-74._x000D_ 9: Bishop PD, Lewis KB, Schultz J, Walker KM. Comparison of recombinant human_ thrombin_ and plasma-derived human alpha_thrombin Semin Thromb Hemost. 2006 Apr;32 Suppl 1:86-97._x000D_ 10: Huntington JA. Thrombin plasticity Biochim Biophys Acta. 2012 Jan;1824(1):246-52. _x000D_ _x000D_ Products Related to Human Gamma Thrombin can be found at Enzymes

Catalog Number: B2013733 (1 mg)

0.15

2

0.5