Products for Research Use Only
RegisterLogin

NSC663284

CAT: 0013-GTR19203746-02Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203746-02Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DA-3003-1 is a cell-permeable, potent, and selective inhibitor of Cdc25 dual-specificity phosphatases (A, B, and C isoforms) . Its ability to disrupt cell cycle progression has demonstrated antitumor activity, making it a valuable chemical probe for studying cell cycle regulation and oncology in both cellular and animal models.
CAS Number
383907-43-5
Product Name Alternative
CDC25A, Cdc25B2, CDC25B2, CDC25C, NSC 663284
Field of Research
Epigenetics & Chromatin, Metabolism Research
Purity
>98%
Bioactivity
Cdc25 Phosphatase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 55 mg/ml) .
Smiles
ClC1=C (NCCN2CCOCC2) C (=O) c2ncccc2C1=O
Molecular Formula
C15H16ClN3O3
Molecular Weight
321.77
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
6-Chloro-7-[[2- (4-morpholinyl) ethyl]amino]-5,8-quinolinedione

Chemical Information

DA-3003-1

6-chloro-7-[2-(4-morpholinyl)ethylamino]quinoline-5,8-dione is a quinolone that is quinoline-5,8-dione substituted by chloro and [2-(morpholin-4-yl)ethyl]amino groups at positions 6 and 7, respectively. It is a potent and irreversible inhibitor of Cdc25 isoforms. It has a role as an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor and an antineoplastic agent. It is a quinolone, a member of p-quinones, an organochlorine compound, an aminoquinoline and a member of morpholines.

CAS Number383907-43-5
PubChem CID379077
IUPAC Name6-chloro-7-(2-morpholin-4-ylethylamino)quinoline-5,8-dione
Molecular FormulaC15H16ClN3O3
Molecular Weight321.76
XLogP1.4
Topological Polar Surface Area71.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count22
Formal Charge0
Complexity488
SMILES
C1COCCN1CCNC2=C(C(=O)C3=C(C2=O)N=CC=C3)Cl
InChI
InChI=1S/C15H16ClN3O3/c16-11-13(18-4-5-19-6-8-22-9-7-19)15(21)12-10(14(11)20)2-1-3-17-12/h1-3,18H,4-9H2
InChIKey
BMKPVDQDJQWBPD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of DA-3003-1
CAS: 383907-43-5
CID: 379077
Formula: C15H16ClN3O3
MW: 321.76
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight321.76
XLogP31.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass321.0880191
Monoisotopic Mass321.0880191
Topological Polar Surface Area71.5 Ų
Heavy Atom Count22
Formal Charge0
Complexity488
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
bs-82193C-01NSC663284

Popular Products