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NSC663284

CAT: 0498-bs-82193C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82193C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. Acts via irreversible oxidation of the catalytic cysteine of CDC254.
Conjugation
Unconjugated
Buffer
Red solid
Storage Conditions
-20°C

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CatalogName
GTR19203746-01NSC663284

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