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YS-121

CAT: 0013-GTR19202368-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19202368-01Size:1 mg
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Description
YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LOX), with IC50 values of 3.4 μM and 6.5 μM, respectively. It dose-dependently inhibits PGE2 production (EC50=12 μM) in IL-1β-stimulated A549 cells, making it a useful research tool for studying inflammation and eicosanoid biology in cellular models.
CAS Number
916482-17-2
Field of Research
Immunology & Inflammation, Metabolism Research
Smiles
N (C1=NC (SC (CCCCCC) C (O) =O) =NC (Cl) =C1) C2=C (C) C (C) =CC=C2
Molecular Formula
C20H26ClN3O2S
Molecular Weight
407.96
Storage Conditions
-20°C
Notes
For research use only.

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