Products for Research Use Only

HTH-01-091

CAT: 0013-GTR19200227-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19200227-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HTH-01-091 is a potent, selective MELK inhibitor (IC50 10.5 nM) with additional activity against kinases including PIM1-3 and RIPK2. This compound serves as a valuable chemical probe for studying MELK function in breast cancer research, enabling both in vitro and in vivo experimental investigations.
CAS Number
2000209-42-5
Product Name Alternative
DYRK, CLK2, MLCK, MELK, HTH 01091, HTH 01-091, HTH01091, HTH-01091, HTH-01-091, HTH01-091, Serine kinase, Serinekinase, threonin kinase, threoninkinase, Pim, RIP kinase, RIPkinase, RIPK2
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.40% (May vary between batches)
Solubility
DMSO:5 mg/mL (10.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2 mM)
Smiles
O=C1N (C2=C3C (=NC=C2CN1) C=CC (=C3) C4=CC (Cl) =C (O) C (Cl) =C4) [C@@H]5CC[C@@H] (CN (C) C) CC5
Molecular Formula
C26H28Cl2N4O2
Molecular Weight
499.43
Storage Conditions
-20°C
Notes
For research use only.

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