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Poloppin

CAT: 0013-GTR19199777-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19199777-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Poloppin is a small molecule modulator of mitotic polo-like kinases that targets mutant KRAS, acting synergistically with the c-MET inhibitor Crizotinib against KRAS-mutant cancer cells. It is applied in oncology research, with in vitro and in vivo studies exploring its efficacy in targeted therapy development.
CAS Number
683808-78-8
Field of Research
Cell Biology, Signal Transduction
Smiles
OC (=O) CCC1=CC=C (N1C1=C (C=CC=C1) C (F) (F) F) C1=CC=C (Br) C=C1
Molecular Formula
C20H15BrF3NO2
Molecular Weight
438.24
Storage Conditions
-20°C
Notes
For research use only.

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