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Ispronicline

CAT: 0013-GTR19197453-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19197453-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ispronicline (TC-1734) is a potent and selective partial agonist of the α4β2 nicotinic acetylcholine receptor (nAChR), exhibiting high affinity (Ki=11 nM) . This small molecule is utilized in research exploring cognitive enhancement, neuroprotection, and antidepressant mechanisms, with applications in both in vitro binding studies and in vivo behavioral models.
CAS Number
252870-53-4
Product Name Alternative
RJR-1734, α4β2 nAChR, TC 01734, TC1734, TC-1734, TC 1734, TC01734, TC-01734, AZD 3480, AZD3480, AZD-3480, Ispronicline
Field of Research
Neuroscience
Purity
96.49% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.53 mM) ; DMSO:50 mg/mL (213.37 mM)
Smiles
CN[C@@H] (C) C\C=C\c1cncc (OC (C) C) c1
Molecular Formula
C14H22N2O
Molecular Weight
234.34
Storage Conditions
-20°C
Notes
For research use only.

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