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AX 048

CAT: 0013-GTR19190810-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19190810-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AX 048 is a potent and selective inhibitor of cytosolic phospholipase A2 (cPLA2α), effectively blocking arachidonic acid release with an XI (50) of 0.022. It demonstrates in vivo efficacy by reducing carrageenan-induced thermal hyperalgesia (ED50 = 1.2 mg/kg) and shows no activity against COX or central cannabinoid receptors at 30 μM, making it a valuable tool for studying eicosanoid-mediated inflammation.
CAS Number
873079-69-7
Field of Research
Metabolism Research
Smiles
C (C (CCCCCCCCCCCCCC) =O) (NCCCC (OCC) =O) =O
Molecular Formula
C22H41NO4
Molecular Weight
383.57
Storage Conditions
-20°C
Notes
For research use only.

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