AX-024

CAT: 0013-GTR19187494-01Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19187494-01Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

AX-024 is a potent and selective orally bioavailable small molecule inhibitor of the TCR-Nck interaction, targeting SH3 domains to suppress T cell activation. With an IC50 of ~1 nM, it effectively reduces pro-inflammatory cytokine production (e.g., IL-6, TNF-α, IFN-γ) and demonstrates low acute toxicity, making it a valuable tool for researching T-cell-mediated diseases in both cellular and animal models.

CAS Number

1370544-73-2

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

COc1ccc2OCC (CN3CCCC3) =C (c3ccc (F) cc3) c2c1

Molecular Formula

C21H22FNO2

Molecular Weight

339.4

Storage Conditions

-20°C

Notes

For research use only.

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A16926-10	AX-024 10mg
A16926-5	AX-024 5mg
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AX-024

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