Products for Research Use Only
RegisterLogin

KR-32568

CAT: 0013-GTR19191306-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19191306-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KR-32568 is a potent and selective NHE-1 inhibitor (IC50: 230 nM) with demonstrated cardioprotective properties. In vitro, it restored cardiac function in ischemic rat hearts, while in vivo administration significantly reduced myocardial infarct size in rat models of ischemia-reperfusion injury.
CAS Number
852146-73-7
Product Name Alternative
Na+/H+-exchanger (NHE), KR 32568, KR32568, KR-32568, SodiumChannel, Sodium Channel
Field of Research
Pharmacology & Drug Discovery
Purity
99.89% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.63 mM) ; DMSO:90 mg/mL (344.5 mM)
Smiles
CC1=C (C=2OC (C (NC (=N) N) =O) =CC2) C=C (F) C=C1
Molecular Formula
C13H12FN3O2
Molecular Weight
261.25
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

KR-32568

Cardioprotective agent; structure in first source

CAS Number852146-73-7
PubChem CID11368995
IUPAC NameN-(diaminomethylidene)-5-(5-fluoro-2-methylphenyl)furan-2-carboxamide
Molecular FormulaC13H12FN3O2
Molecular Weight261.25
XLogP2.4
Topological Polar Surface Area94.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count19
Formal Charge0
Complexity371
SMILES
CC1=C(C=C(C=C1)F)C2=CC=C(O2)C(=O)N=C(N)N
InChI
InChI=1S/C13H12FN3O2/c1-7-2-3-8(14)6-9(7)10-4-5-11(19-10)12(18)17-13(15)16/h2-6H,1H3,(H4,15,16,17,18)
InChIKey
DTLDHYBZLVASJQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of KR-32568
CAS: 852146-73-7
CID: 11368995
Formula: C13H12FN3O2
MW: 261.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight261.25
XLogP32.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass261.09135480
Monoisotopic Mass261.09135480
Topological Polar Surface Area94.6 Ų
Heavy Atom Count19
Formal Charge0
Complexity371
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19240479-01KR-40795
GTR19197354-01KR-30450
GTR19197353-01KR-31378
GTR19184447-01KR-39038
GTR19262131-01KR-27370
GTR19218376-01KR-27425
GTR19210209-01KR 60436
GTR19240432-01KR-31080
GTR19164518-01KR-33493
GTR19209088-01KR-67607

Alternative Products

CatalogName
HY-118778-01KR-32568
FB158572-01KR- 33494
HY-179469KR-27452
T69802-01KR 60436
T27738-01KR-30450
T64266-01KR-39038
T81973-01KR-27425
TQ0220-01KR-33493
HY-169300KR-40795
MBS5777443KR-31378

Popular Products