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S65487 hydrochloride

CAT: 0013-GTR19190412-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19190412-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S65487 hydrochloride is a potent, selective Bcl-2 inhibitor effective against common resistance mutations like G101V and D103Y, with minimal affinity for MCL-1, BFL-1, and BCL-XL. It demonstrates pro-apoptotic and anticancer activity in cellular assays and has shown efficacy in hematological malignancy xenograft models.
CAS Number
1644543-95-2
Field of Research
Cell Biology
Smiles
Cl.Cc1c (cc (C#N) n1C) N (C (=O) c1cc (-c2cc (Cl) ccc2C (=O) N2Cc3ccccc3C[C@H]2CN2CCOCC2) n (C) c1C) c1ccc (O) cc1
Molecular Formula
C41H42Cl2N6O4
Molecular Weight
753.73
Storage Conditions
-20°C
Notes
For research use only.

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