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S65487 hydrochloride

CAT: 0931-T39135-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T39135-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1644543-95-2
Target
Others, Apoptosis, Bcl-2 Family
Related Pathways
Apoptosis, Others
Bioactivity
S65487 (VOB560) hydrochloride, a potent and selective Bcl-2 inhibitor, is effective against BCL-2 mutations, including G101V and D103Y, while exhibiting poor affinity for MCL-1, BFL-1, and BCL-XL. This compound induces apoptosis and possesses anticancer activities.
Smiles
Cl.Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1
Molecular Formula
C41H42Cl2N6O4
Molecular Weight
753.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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