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AM404

CAT: 0013-GTR19189558-01Size: 5 mg (126.4 mM x 100 ul in ethanol)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19189558-01Size:5 mg (126.4 mM x 100 ul in ethanol)
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Description
AM404 is a bioactive paracetamol metabolite that acts as an endocannabinoid reuptake inhibitor and TRPV1 activator. It exhibits neuroprotective and anticancer properties by blocking anandamide transport, inhibiting COX, NF-κB, and NFAT signaling. This activity reduces neuroblastoma cell migration and invasiveness in vitro and suppresses prostaglandin synthesis in microglia.
CAS Number
183718-77-6
Field of Research
Pharmacology & Drug Discovery
Smiles
N (C (CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC) =O) C1=CC=C (O) C=C1
Molecular Formula
C26H37NO2
Molecular Weight
395.58
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

AM404

AM404 is an anilide.

CAS Number183718-77-6
PubChem CID6604822
IUPAC Name(5Z,8Z,11Z,14Z)-N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide
Molecular FormulaC26H37NO2
Molecular Weight395.6
XLogP7.2
Topological Polar Surface Area49.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count15
Heavy Atom Count29
Formal Charge0
Complexity511
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NC1=CC=C(C=C1)O
InChI
InChI=1S/C26H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26(29)27-24-20-22-25(28)23-21-24/h6-7,9-10,12-13,15-16,20-23,28H,2-5,8,11,14,17-19H2,1H3,(H,27,29)/b7-6-,10-9-,13-12-,16-15-
InChIKey
IJBZOOZRAXHERC-DOFZRALJSA-N
Chemical Structure
2D Structure
2D structure of AM404
CAS: 183718-77-6
CID: 6604822
Formula: C26H37NO2
MW: 395.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight395.6
XLogP37.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count15
Exact Mass395.282429423
Monoisotopic Mass395.282429423
Topological Polar Surface Area49.3 Ų
Heavy Atom Count29
Formal Charge0
Complexity511
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count4
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
E8036AM404
HY-W777527-01AM404-d4

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