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Oritinib mesylate

CAT: 0013-GTR19189344Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189344Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oritinib mesylate (SH-1028) is a potent, orally bioavailable, and irreversible EGFR inhibitor with an IC50 of 18 nM. It effectively targets both EGFR-sensitizing and T790M resistance mutations, demonstrating robust anti-proliferative activity in vitro and promising efficacy in preclinical in vivo tumor models.
CAS Number
2180164-79-6
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
CS (O) (=O) =O.COc1cc (N (C) CCN (C) C) c (NC (=O) C=C) cc1Nc1nccc (n1) -c1c2CCCCn2c2ccccc12
Molecular Formula
C32H41N7O5S
Molecular Weight
635.78
Storage Conditions
-20°C
Notes
For research use only.

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