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M-808

CAT: 0013-GTR19189174-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189174-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M-808 is a potent, covalent small-molecule inhibitor that disrupts the Menin-MLL protein-protein interaction with high affinity (IC50 = 2.6 nM) . It is a valuable chemical probe for researching MLL-rearranged leukemias and has demonstrated utility in both in vitro biochemical assays and in vivo xenograft models.
CAS Number
2377335-74-3
Field of Research
Epigenetics & Chromatin
Smiles
[H][C@@]1 (CCC[C@@H]1NC (=O) OC) [C@@] (CN1CCC1) (C1CCN (CC2CN (C2) c2ccc (cc2) S (=O) (=O) C2CN (C2) C (=O) \C=C\CN2CCCCC2) CC1) c1cccc (F) c1
Molecular Formula
C45H63FN6O5S
Molecular Weight
819.09
Storage Conditions
-20°C
Notes
For research use only.

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