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NHE3-IN-3

CAT: 0013-GTR19187062-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19187062-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NHE3-IN-3 is a potent and selective small molecule inhibitor of the Na+/H+ exchanger isoform 3 (NHE3), demonstrating pIC50 values of 6.2 and 6.6 against human and rat targets, respectively. It is characterized by excellent oral bioavailability (98% in rats), making it a valuable pharmacological tool for investigating NHE3 function in renal physiology, acid-base balance, and related disorders in both in vitro and in vivo models.
CAS Number
543734-50-5
Field of Research
Pharmacology & Drug Discovery
Smiles
CN1CC (C=2C (C1) =C (Cl) C=C (Cl) C2) C3=CC (S (N) (=O) =O) =CC=C3
Molecular Formula
C16H16Cl2N2O2S
Molecular Weight
371.28
Storage Conditions
-20°C
Notes
For research use only.

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