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NHE3 Antibody (APC)

CAT: 0013-GTR18029418Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18029418Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to NHE3 (APC) . Sodium-hydrogen exchanger 3 (NHE3; Slc9a3) is an epithelial transport protein that carries out 1:1 exchange of Na+ and H+ across the plasma membrane. It is apically located in the proximal tubule of the kidney, the thick ascending limb of the kidney, and in small intestine. NHE3 is phosphorylated and regulated by multiple kinases including PKA, SGK1 and CK2. It can be phosphorylated by calyculin A, and dephosphorylated by PP1 catalytic subunit in vitro..
Product Name Alternative
Sodium / Hydrogen Exchanger 3, SLC9A3, Na+/H+ exchanger 3, isoform 3, Solute carrier family 9 member 3, NHE3MGC126720, MGC126718, solute carrier family 9 (sodium/hydrogen exchanger) member 3, NHE-3, Na (+) /H (+) exchanger 3, Sodium/hydrogen exchanger 3
UniProt
P26433
Reactivity
Mouse, Rat
Immunogen
Synthetic peptide mapping to AA 809 to 831 of rat sequence
Target
NHE3
Clonality
Polyclonal
Conjugation
APC
Field of Research
Cancer Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purification
Protein A Purified
Concentration
1 mg/ml
Dilution
WB (1:1000) ; IHC (1:25)
Molecular Weight
84kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of HNE3 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_036786
Host or Source
Rabbit
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Entrez
24784

UniProtKB · P26433

Sodium/hydrogen exchanger 3

SL9A3_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
P26433
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Slc9a3
Protein existence
1: Evidence at protein level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Biological process

AntiportIon transportSodium transportTransport

Cellular component

Cell membraneEndosomeMembrane

PTM

Phosphoprotein

Technical term

Reference proteome

Domain

SignalTransmembraneTransmembrane helix

Ligand

Sodium

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